Electron Microscopic Cytochemistry of Adenylyl Cyclase Activity in Mouse Spermatozoa
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چکیده
منابع مشابه
Characterization of mouse heart adenylyl cyclase.
Chronic heart failure is one of the most frequent causes of death in humans. Knockout of type 5 adenylyl cyclase (AC) in mice causes longevity and protection from cardiomyopathy, and an AC5 inhibitor reduces beta-adrenoceptor-stimulated Ca(2+) inward currents in isolated mouse cardiomyocytes. These data indicate that selective AC5 inhibitors may be beneficial in chronic heart failure. Therefore...
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In mammals, Ca2+ and HCO3- ions play a critical role in the regulation of sperm function, most likely by regulation of cAMP levels. Mammalian germ cells contain a soluble adenylyl cyclase (sAC) with properties distinct from the well characterized membrane-bound enzymes Here we investigated whether the cyclase expressed in mature spermatozoa has the properties of sAC and whether it is regulated ...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2004
ISSN: 0022-1554,1551-5044
DOI: 10.1369/jhc.3b6141.2004